Ayurvedic Approach to Diabetes Mellitus Associated With Pancreatitis: A Case Study
DOI:
https://doi.org/10.48165/pimrj.2025.2.2.10Keywords:
Diabetes associated with pancreati tis, Madhumeha, Agni Dushti, Pan chakarma, Basti, Nasyam, Shiropi chuAbstract
Diabetes associated with pancreatitis is an increasingly recognized health concern, primarily arising secondary to pancreatic diseases, with chronic pancreatitis being the most prevalent cause. In Ayurvedic terms, diabetes mellitus (Prameha) is associated with Kapha and Pitta vitiation, whereas pancreatitis is linked to aggravated Pitta disrupting Agni (digestive fire) and leading to Amaaccumulation. Ayurvedic management integrates di etary modifications, Ayurvedic formulations, and Panchakarma therapies to restore metabolic balance and enhance pancreatic function. This study presents the case of a 29-year-old male diagnosed with Diabetes Mellitus associated with pancreatitis, who sought treatment at Jeena Sikho Lifecare Limited Hospital, Derabassi, Punjab. He underwent Panchakarma thera pies, including Awagah Swedan, Madhu Tailik Basti, Shiropichu with Brah mi oil, and Nasyam with Anutaila, alongside Ayurvedic formulations. Fol lowing Ayurvedic treatment, the patient experienced significant symptom relief, improved glycemic control, and better laboratory parameters, includ ing reduced HbA1C levels and improved liver enzyme markers. These find ings highlight the potential of Ayurvedic interventions in managing diabetes associated with pancreatitis. However, further clinical trials are necessary to validate these outcomes and establish standardized treatment protocols for enhanced patient care.
References
Hart PA, Bradley D, Conwell DL, Dungan K, Krishna SG, Wyne K, et al. Diabetes following acute pancreatitis. Lancet Gastroenterol Hepatol. 2021 Aug;6(8):668–675.
Batta A. Acute pancreatitis and diabetes mellitus—A relation. Middle East Res J Med Sci. 2024;4(3):57–60.
Zahariev OJ, Bunduc S, Kovács A, Demeter D, Havelda L, Budai BC, et al. Risk factors for diabetes mellitus after acute pancreatitis: A systematic review and meta-analysis. Front Med (Lausanne). 2024 Jan 9;10:1257222. doi:10.3389/fmed.2023.1257222. PMID: 38264039; PMCID: PMC10803425.
Wynne K, Devereaux B, Dornhorst A. Diabetes of the exocrine pancreas. J Gastroenterol Hepatol. 2019 Feb;34(2):346–354.
Lee YK, Huang MY, Hsu CY, Su YC. Bidirectional relationship between diabetes and acute pancreatitis: A population-based cohort study in Taiwan. Medicine (Baltimore). 2016 Jan;95(2):e2448. doi:10.1097/MD.0000000000002448. PMID: 26765434; PMCID: PMC4718260.
Gonzalez-Perez A, Schlienger RG, Rodríguez LA. Acute pancreatitis in association with type 2 diabetes and antidiabetic drugs: A population-based cohort study. Diabetes Care. 2010 Dec;33(12):2580–2585. doi:10.2337/dc10-0842. PMID: 20833867; PMCID: PMC2992194.
Manrai M, Singh AK, Birda CL, Shah J, Dutta A, Bhadada SK, et al. Diabetes mellitus as a consequence of acute severe pancreatitis: Unraveling the mystery. World J Diabetes. 2023 Aug 15;14(8):1212–1225. doi:10.4239/wjd.v14.i8.1212. PMID: 37664472; PMCID: PMC10473947.
Noel RA, Braun DK, Patterson RE, Bloomgren GL. Increased risk of acute pancreatitis and biliary disease observed in patients with type 2 diabetes: A retrospective cohort study. Diabetes Care. 2009 May 1;32(5):834–838. doi:10.2337/dc08-1755.
Aune D, MahAmat-Saleh Y, Norat T, Riboli E. Diabetes mellitus and the risk of pancreatitis: A systematic review and meta-analysis of cohort studies. Pancreatology. 2020 Jun;20(4):602–607.
Śliwińska-Mossoń M, Bil-Lula I, Marek G. The cause and effect relationship of diabetes after acute pancreatitis. Biomedicines. 2023;11(3):667. doi:10.3390/biomedicines11030667.
Shen HN, Lu CL, Li CY. Effect of diabetes on severity and hospital mortality in patients with acute pancreatitis: A national population-based study. Diabetes Care. 2012 May 1;35(5):1061–1066.
Lu X, Xie Q, Pan X, et al. Type 2 diabetes mellitus in adults: Pathogenesis, prevention and therapy. Signal Transduct Target Ther. 2024;9:262. doi:10.1038/s41392-024-01951-9.
Singh N. Harnessing the power of Ayurveda for diabetes management: A narrative review. J Clin Diagn Res. 2024 Jun;18(6).
Dabas R, Tewari P. Correlation of Prameha (Madhumeha) with diabetes mellitus. Indian J Agric Allied Sci. 2016.
Thacker NS, Monapara K, Soni SA. Ayurvedic management of chronic pancreatitis – Jirna Pittodara: A single case study. World J Pharm Res. 2022;11(8):969–976.
Dhote N, Bandapalle DN, Bandapalle MD. An Ayurvedic management on pancreatitis: A case study. Afr J Biomed Res. 2025;28(2s):1447–1452.
Raj M. Ayurvedic management of pancreatic disorders: An overview. Pancreat Disord Ther. 2024;14:324.
Modak M, Dixit P, Londhe J, Ghaskadbi S, Devasagayam TP. Indian herbs and herbal drugs used for the treatment of diabetes. J Clin Biochem Nutr. 2007 May;40(3):163–173. doi:10.3164/jcbn.40.163. PMID: 18398493; PMCID: PMC2275761.
Suman M, Pradeep KM. Panchakarma procedures for a healthy life that can be performed at home. J Ayu Int Med Sci. 2023;8(12):150–160. Available from: https://jaims.in/jaims/article/view/2853
Chowdhury BR. Reversal of type 1 diabetes by plant-based diet. Int J Appl Dent Sci. 2023;9(1).
Pandey A, Azad AS, Bhardwaj A, Thakur G, Prakash G. Effectiveness of Gravitational Resistance and Diet (GRAD) system in reversing chronic kidney disease (CKD) among dialysis patients. Dayanand Ayurvedic College, Shridhar University [Internet]. 2022. Available from: https://davAyurveda.com/wp-content/uploads/2022/10/j-GRAD-System-Paper-FINALMar-27-2.pdf
Rathee D, Borannavar S, Desai AS. Madhutailika Basti: A boon in Madhumeha management with special reference to diabetes mellitus – A single case study. J Ayurveda Integr Med Sci. 2022.
Gupta AK, Gupta T. Standard operative procedure & probable mode of action of Shiropichu.
Fatima U, Roy S, Ahmad S, Ali S, Elkady WM, Khan I, et al. Pharmacological attributes of Bacopa monnieri extract: Current updates and clinical manifestation. Front Nutr. 2022 Aug 18;9:972379.
Bansal C, Shukla U. Preventive Nasya scope and challenges: Review. Int J Ayurveda Pharm Res. 2019;7(12):53–57.
Panwar D, Kumar A, Sharma D. Analytical study of Anu Taila: An Ayurvedic oil-based formulation. World J Pharm Pharm Sci. 2023;785. doi:10.20959/wjpps20234-24468.
Sawarkar G, Sawarkar P. Ayurvedic management of chronic pancreatitis in adolescent girl: A case report. J Pharm Res Int. 2021;33(33B):58–67. doi:10.9734/jpri/2021/v33i33B31797.
Meena J, Mishra PK, Sharma I, Sharma B, Rani P. Diabetes mellitus – An Ayurvedic perspective. AYUSHDHARA. 2023;10(Suppl 4):18–23. doi:10.47070/ayushdhara.v10iSuppl4.1336.
Raina T, Saini S, Srivastava A, Manglesh R, Sharma D. Role of diet and lifestyle in the prevention of Madhumeha. Int J Ayurveda Pharm Res. 2017;5(5):89–92.
Pandey PK. Charak Samhita, Volume 1, Nidan Sthana, Prameha Nidan Adhyaya, 4/37. Varanasi: Chaukhambha Bharti Academy; 2014. p. 638.

