Age-Related Dynamics of Anti-Müllerian Hormone and its Correlation with Antral Follicle Count in Growing Heifers

Authors

  • Prachi Sharma Department of Veterinary Gynaecology & Obstetrics, College of Veterinary Sciences and Animal Husbandry, Kamdhenu University, Anand-388001, Gujarat, India
  • Kamlesh K Hadiya Professor, Department of Veterinary Gynaecology & Obstetrics, College of Veterinary Sciences and Animal Husbandry, KU, Anand-388001, Gujarat, India.
  • Siddhartha S Layek In-Vitro Fertilization Facilities, National Dairy Development Board, Anand-388001, Gujarat, India
  • Prakash G Koringa Department of Veterinary Biotechnology, College of Veterinary Sciences and Animal Husbandry, Kamdhenu University, Anand-388001, Gujarat, India
  • Sanket P Patil In-Vitro Fertilization Facilities, National Dairy Development Board, Anand-388001, Gujarat, India
  • Kathan B Raval In-Vitro Fertilization Facilities, National Dairy Development Board, Anand-388001, Gujarat, India
  • Bhautik N Saripadiya Department of Veterinary Gynaecology & Obstetrics, College of Veterinary Sciences and Animal Husbandry, Kamdhenu University, Anand-388001, Gujarat, India

DOI:

https://doi.org/10.48165/ijvsbt.21.6.05

Keywords:

Age-related dynamics, Anti-Müllerian hormone, Antral follicle count, Correlation, Growing heifers

Abstract

The profitability of the dairy industry relies heavily on reproductive efficiency and genetic improvement, particularly in countries where  dairy farming is vital for the economy. This study aimed to evaluate the relationship between Anti-Müllerian hormone (AMH) levels and  antral follicle count (AFC) in female calves as potential biomarkers for predicting reproductive success in advanced breeding programs.  A total of 31 female calves of indigenous and crossbred cattle breeds, aged six months, were selected and monitored over one year,  with blood samples collected at 6, 12, and 18 months to assess AMH levels. Upon reaching 18 months, ultrasound examinations were  performed to determine AFC. Based on the median follicle count of 34.40, irrespective of genetic makeup, the animals were divided  into High AFC (n=15, 50.37±3.08) and Low AFC (n=16, 27.25±1.52) groups. Results indicated a significant decline in AMH levels over  age. Mean AMH level decreased from 2.53±0.29 ng/mL at 6 months to 1.79±0.14 ng/mL at 18 months (p<0.05). Notably, higher AMH  concentrations were consistently associated with greater AFC throughout the age groups (p<0.05), highlighting AMH’s potential as an  early predictor of reproductive performance. The findings underscore the importance of AMH as a valuable biomarker in selecting heifers  for in vitro embryo production programs at an early age, ultimately enhancing the efficiency of breeding strategies in the dairy industry.

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Author Biography

  • Kamlesh K Hadiya, Professor, Department of Veterinary Gynaecology & Obstetrics, College of Veterinary Sciences and Animal Husbandry, KU, Anand-388001, Gujarat, India.

     

     

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Published

2025-11-07

How to Cite

Sharma, P., K Hadiya, K., S Layek, S., G Koringa, P., P Patil, S., B Raval, K., & N Saripadiya, B. (2025). Age-Related Dynamics of Anti-Müllerian Hormone and its Correlation with Antral Follicle Count in Growing Heifers . Indian Journal of Veterinary Sciences and Biotechnology, 21(6), 27-31. https://doi.org/10.48165/ijvsbt.21.6.05