Clinical Studies on Sedative Effect of Butorphanol and Buprenorphine in Bovine
DOI:
https://doi.org/10.48165/ijvsbt.21.4.13Keywords:
Bovine, Buprenorphine, Butorphanol, Guaifenesin, Isoflurane, KetamineAbstract
The present clinical study was conducted on 24 bovines scheduled for major surgical procedures. The animals were randomly divided into four groups (n=6 each) to evaluate the preanaesthetic effect of Butorphanol and Buprenorphine. Animals in groups I and II, were premedicated with Butorphanol (0.02 mg/kg, IV), while in groups III and IV, Buprenorphine (0.006 mg/kg, IV) was used. Induction agent used in all 4 groups was a mixture of Ketamine HCl (1 gm) and Guaifenesin (25 gm) diluted in 500 mL of 5% dextrose and given intravenously “till effect”. All animals were orotracheally intubated after induction of anaesthesia. In group I and III, Isoflurane and 100 % oxygen mixture was used as per demand of the cases, while a double drip of Ketamine and Guaifenesin mixture was given in groups II and IV to achieve the desired depth of surgical anaesthesia throughout the period of surgery. Evaluation of anaesthetic efficacy was made by determining the dose of induction agent (total dose), duration of maintenance anaesthesia (min), duration of surgery (min) and recovery time (min). A combination of Butorphanol and Buprenorphine provided good to excellent quality of sedation as compared to Butorphanol alone in bovine. Buprenorphine showed potent dose sparing effect on induction and maintenance dose of Ketamine and Guaifenesin or Isoflurane than Butorphanol in bovine.
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